Proteomics allows a better understanding of the physiopathology of alzheimersdisease
This statement is suggested and supported by:
an amazing and comprehensive paper(1) by Sruti Rayaprolu et al. from Emory University school of medicine in Atlanta explains how and why proteomics – the study of the entire set of proteins present in a cell, a tissue, an organ or an organism at a given time and of its evolution over time – could revolutionize the understanding of the pathogenesis, diagnostic and disease monitoring (through biomarkers that go far beyond amyloid and Tau proteins) and consequently lead to new therapeutic approaches.
(1) Rayaprolu S et al. Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau. Neuropsychopharmacology. 2021 Jan;46(1):98-115. doi: 10.1038/s41386-020-00840-3. Epub 2020 Sep 8. PMID: 32898852; PMCID: PMC7689445.